Pilot study investigating the prevalence of oral Human Papilloma Viral (HPV) infection in young adults

Journal article

Knight, Gillian L., Needham, Louise, Roberts, Sally and Ward, Derek 2016. Pilot study investigating the prevalence of oral Human Papilloma Viral (HPV) infection in young adults. Public Health. https://doi.org/10.1016/j.puhe.2015.12.006
AuthorsKnight, Gillian L., Needham, Louise, Roberts, Sally and Ward, Derek
Abstract

The rates of HPV related Head and neck squamous cell carcinomas (HNSCC) within the UK have been steadily increasing, particular in young white men. The reasons behind this increase have not been elucidated, but maybe linked to higher prevalence of oral HPV infection in men. This pilot study aimed to establish a reproducible HPV oral screening method to investigate the rate of oral HPV infection in young healthy adults. The study found that 4% (3 men and 2 women)of the study cohort (N = 124) had a detectable oral HPV infection, which was found to be comparable with US based investigations. An interesting finding of this pilot study was that 80% of the HPV infected individuals smoked, and one of the HPV infected females had received the HPV vaccination. This preliminary data highlights the need for further investigation into the rates of oral HPV infection in the healthy community and to determine what particular lifestyle choices could be risk factors for infection and how the HPV vaccination programme will affect HPV infectivity levels in both women and men.

The rates of HPV related Head and neck squamous cell carcinomas
(HNSCC) within the UK have been steadily increasing, particular in young
white men. The reasons behind this increase have not been elucidated, but
maybe linked to higher prevalence of oral HPV infection in men. This
pilot study aimed to establish a reproducible HPV oral screening method
to investigate the rate of oral HPV infection in young healthy adults.
The study found that 4% (3 men and 2 women)of the study cohort (N = 124)
had a detectable oral HPV infection, which was found to be comparable
with US based investigations. An interesting finding of this pilot study
was that 80% of the HPV infected individuals smoked, and one of the HPV
infected females had received the HPV vaccination. This preliminary data
highlights the need for further investigation into the rates of oral HPV
infection in the healthy community and to determine what particular
lifestyle choices could be risk factors for infection and how the HPV
vaccination programme will affect HPV infectivity levels in both women
and men.

KeywordsHuman Papilloma Virus (HPV); Head and neck cancer; Epidemiology; Oral infection; Vaccination
Year2016
JournalPublic Health
PublisherElsevier
ISSN00333506
Digital Object Identifier (DOI)https://doi.org/10.1016/j.puhe.2015.12.006
Web address (URL)http://hdl.handle.net/10545/620686
hdl:10545/620686
Publication dates03 Feb 2016
Publication process dates
Deposited01 Nov 2016, 16:36
Accepted14 Dec 2015
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Archived with thanks to Public Health

ContributorsUniveristy of Derby
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