The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line.
Journal article
Asher, Viren, Warren, Averil, Shaw, Robert, Sowter, Heidi M., Bali, Anish and Khan, Raheela 2011. The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. Cancer cell international. https://doi.org/10.1186/1475-2867-11-6
| Authors | Asher, Viren, Warren, Averil, Shaw, Robert, Sowter, Heidi M., Bali, Anish and Khan, Raheela |
|---|---|
| Abstract | The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death. The role of these channels in the onset and progression of ovarian cancer is unknown. An understanding of mechanism by which Eag and HERG channels affect cell proliferation in ovarian cancer cells is required and therefore we investigated their role in cell proliferation and their effect on the cell cycle and apoptosis of ovarian cancer cells. |
| Keywords | Ovarian cancer; Potassium channels; Eag1 |
| Year | 2011 |
| Journal | Cancer cell international |
| ISSN | 1475-2867 |
| Digital Object Identifier (DOI) | https://doi.org/10.1186/1475-2867-11-6 |
| Web address (URL) | http://hdl.handle.net/10545/225603 |
| hdl:10545/225603 | |
| Publication dates | Mar 2011 |
| Publication process dates | |
| Deposited | 23 May 2012, 14:50 |
| Rights | Archived with thanks to Cancer cell international |
| Contributors | Royal Derby Hospital, School of Graduate Entry Medicine and Health and University of Derby, Faculty of Education, Health and Science |
| File | File Access Level Open |
| File | File Access Level Open |
| File | File Access Level Open |
| File | File Access Level Open |
Permalink -
https://repository.derby.ac.uk/item/950x2/the-role-of-eag-and-herg-channels-in-cell-proliferation-and-apoptotic-cell-death-in-sk-ov-3-ovarian-cancer-cell-line
Download files
27
total views10
total downloads1
views this month0
downloads this month
Export as
Related outputs
The PAX8 cistrome in epithelial ovarian cancer.
Adler, Emily K., Corona, Rosario I., Lee, Janet M., Rodriguez-Malave, Norma, Mhawech-Fauceglia, Paulette, Sowter, Heidi M., Hazelett, Dennis J., Lawrenson, Kate and Gayther, Simon A. 2017. The PAX8 cistrome in epithelial ovarian cancer. Oncotarget. https://doi.org/10.18632/oncotarget.22718Targeting Src in endometriosis-associated ovarian cancer
Manek, Roxanne, Pakzamir, Elham, Mhawech-Fauceglia, Paulette, Pejovic, Tanja, Sowter, Heidi M., Gayther, Simon A. and Lawrenson, Kate 2016. Targeting Src in endometriosis-associated ovarian cancer. Oncogenesis. https://doi.org/10.1038/oncsis.2016.54
Pilot study : can inspiratory muscle training relieve symptoms ff dyspnoea and improve quality of life for advanced cancer patients ?: 1872 Board #24 June 2, 3: 30 PM - 5: 00 PM.
Lindley, Martin R., Faghy, Mark, Sowter, Heidi M. and Mickleborough, Timothy D. 2016. Pilot study : can inspiratory muscle training relieve symptoms ff dyspnoea and improve quality of life for advanced cancer patients ?: 1872 Board #24 June 2, 3: 30 PM - 5: 00 PM. Wolters Kluwer. https://doi.org/10.1249/01.mss.0000486545.72377.ea"I'm 100% for it! I'm a convert!" Women's experiences of a yoga programme during treatment for gynaecological cancer; an interpretative phenomenological analysis
Archer, Stephanie, Phillips, Elly, Montague, Jane, Bali, Anish and Sowter, Heidi M. 2014. "I'm 100% for it! I'm a convert!" Women's experiences of a yoga programme during treatment for gynaecological cancer; an interpretative phenomenological analysis. Complementary therapies in medicine. https://doi.org/10.1016/j.ctim.2014.12.003"I'm 100% for it! I'm a convert!": Women's experiences of a yoga programme during treatment for gynaecological cancer; an interpretative phenomenological analysis.
Archer, Stephanie, Phillips, Elly, Montague, Jane, Bali, Anish and Sowter, Heidi M. 2015. "I'm 100% for it! I'm a convert!": Women's experiences of a yoga programme during treatment for gynaecological cancer; an interpretative phenomenological analysis. Complementary therapies in medicine. https://doi.org/10.1016/j.ctim.2014.12.003Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the Secretomes of three-dimensional genetic models of ovarian carcinogenesis.
Lawrenson, Kate, Mhawech-Fauceglia, Paulette, Worthington, Jenny, Spindler, Tassja J., O'Brien, Darragh, Lee, Janet M., Spain, Georgia, Sharifian, Maryam, Wang, Guisong, Darcy, Kathleen M., Pejovic, Tanja, Sowter, Heidi M., Timms, John F. and Gayther, Simon A. 2014. Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the Secretomes of three-dimensional genetic models of ovarian carcinogenesis. International Journal of Cancer. https://doi.org/10.1002/ijc.29197