The Eag potassium channel as a new prognostic marker in ovarian cancer.

Journal article

Asher, Viren, Khan, Raheela, Warren, Averil, Shaw, Robert, Schalkwyk, Gerhard V., Bali, Anish and Sowter, Heidi M. 2010. The Eag potassium channel as a new prognostic marker in ovarian cancer. Diagnostic pathology. https://doi.org/10.1186/1746-1596-5-78
AuthorsAsher, Viren, Khan, Raheela, Warren, Averil, Shaw, Robert, Schalkwyk, Gerhard V., Bali, Anish and Sowter, Heidi M.
Abstract

Ovarian cancer is the second most common cancer of the female genital tract in the United Kingdom (UK), accounting for 6% of female deaths due to cancer. This cancer is associated with poor survival and there is a need for new treatments in addition to existing chemotherapy to improve survival. Potassium (K+) channels have been shown to be overexpressed in various cancers where they appear to play a role in cell proliferation and progression.

KeywordsOvarian cancer; Potassium channels; Eag1; Adult; Aged; Aged, 80 and over; Biopsy; Cell line, tumor; Cell proliferation; Ether-a-go-go potassium channels; Female; Humans; Immunohistochemistry; Kaplan-Meier estimate; Middle aged; Neoplasm staging; Ovarian neoplasms; Potassium channel blockers; Time factors; Tissue array analysis; Treatment outcome; Tumor markers, biological; Up-regulation; Young adult
Year2010
JournalDiagnostic pathology
ISSN1746-1596
Digital Object Identifier (DOI)https://doi.org/10.1186/1746-1596-5-78
Web address (URL)http://hdl.handle.net/10545/225604
hdl:10545/225604
Publication dates2010
Publication process dates
Deposited23 May 2012, 14:55
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ContributorsRoyal Derby Hospital, School of Graduate Entry Medicine and Health, Department of Obstetrics and Gynaecology and University of Derby
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