The Eag potassium channel as a new prognostic marker in ovarian cancer.
Journal article
Asher, Viren, Khan, Raheela, Warren, Averil, Shaw, Robert, Schalkwyk, Gerhard V., Bali, Anish and Sowter, Heidi M. 2010. The Eag potassium channel as a new prognostic marker in ovarian cancer. Diagnostic pathology. https://doi.org/10.1186/1746-1596-5-78
| Authors | Asher, Viren, Khan, Raheela, Warren, Averil, Shaw, Robert, Schalkwyk, Gerhard V., Bali, Anish and Sowter, Heidi M. |
|---|---|
| Abstract | Ovarian cancer is the second most common cancer of the female genital tract in the United Kingdom (UK), accounting for 6% of female deaths due to cancer. This cancer is associated with poor survival and there is a need for new treatments in addition to existing chemotherapy to improve survival. Potassium (K+) channels have been shown to be overexpressed in various cancers where they appear to play a role in cell proliferation and progression. |
| Keywords | Ovarian cancer; Potassium channels; Eag1; Adult; Aged; Aged, 80 and over; Biopsy; Cell line, tumor; Cell proliferation; Ether-a-go-go potassium channels; Female; Humans; Immunohistochemistry; Kaplan-Meier estimate; Middle aged; Neoplasm staging; Ovarian neoplasms; Potassium channel blockers; Time factors; Tissue array analysis; Treatment outcome; Tumor markers, biological; Up-regulation; Young adult |
| Year | 2010 |
| Journal | Diagnostic pathology |
| ISSN | 1746-1596 |
| Digital Object Identifier (DOI) | https://doi.org/10.1186/1746-1596-5-78 |
| Web address (URL) | http://hdl.handle.net/10545/225604 |
| hdl:10545/225604 | |
| Publication dates | 2010 |
| Publication process dates | |
| Deposited | 23 May 2012, 14:55 |
| Rights | Archived with thanks to Diagnostic pathology |
| Contributors | Royal Derby Hospital, School of Graduate Entry Medicine and Health, Department of Obstetrics and Gynaecology and University of Derby |
| File | File Access Level Open |
| File | File Access Level Open |
| File | File Access Level Open |
| File | File Access Level Open |
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