Effect of exercise interventions on perceived fatigue in people with multiple sclerosis: synthesis of meta-analytic reviews
Journal article
Authors | Safari, Reza, Van der Linden, Marietta L. and Mercer, Tom H. |
---|---|
Abstract | Although exercise training has been advocated as a nonpharmacological treatment for multiple sclerosis (MS) related fatigue, no consensus exists regarding its effectiveness. To address this, we collated meta-analytic reviews that explored the effectiveness of exercise training for the treatment of MS-related fatigue. We searched five online databases for relevant reviews, published since 2005, and identified 172 records. Five reviews were retained for systematic extraction of information and evidence quality analysis. Although our review synthesis indicated that exercise training interventions have a moderate effect on fatigue reduction in people with MS, no clear insight was obtained regarding the relative effectiveness of specific types or modes of exercise intervention. Moreover, Grading of Recommendation Assessment, Development and Evaluation revealed that the overall quality of evidence emanating from these five reviews was ‘very low’. |
Keywords | Exercise; Multiple Sclerosis; Fatigue; Review |
Year | 2017 |
Journal | Neurodegenerative Disease Management |
Publisher | Future Medicine |
ISSN | 17582024 |
17582032 | |
Digital Object Identifier (DOI) | https://doi.org/10.2217/nmt-2017-0009 |
Web address (URL) | http://hdl.handle.net/10545/621770 |
hdl:10545/621770 | |
Publication dates | 20 Jun 2017 |
Publication process dates | |
Deposited | 27 Jul 2017, 12:41 |
Accepted | 24 Apr 2017 |
Rights | Archived with thanks to Neurodegenerative Disease Management |
Contributors | University of Derby, Queen Margaret University, Centre for Health & Social Care Research, College of Health & Social Care, University of Derby, Derby, DE22 1GB, UK, Centre for Health & Social Care Research, College of Health & Social Care, University of Derby, Derby, DE22 1GB, UK and Centre for Health & Social Care Research, College of Health & Social Care, University of Derby, Derby, DE22 1GB, UK |
File | File Access Level Open |
File | File Access Level Open |
https://repository.derby.ac.uk/item/92997/effect-of-exercise-interventions-on-perceived-fatigue-in-people-with-multiple-sclerosis-synthesis-of-meta-analytic-reviews
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