Isaac Shawa

NameIsaac Shawa
Job titleLecturer in Clinical Microbiology
Research instituteCollege of Science and Engineering
ORCIDhttps://orcid.org/0000-0001-5236-6467

Research outputs

Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis

Shawa, I.T, Sheridan, D.A, Shawa, I.T, Thomas, E.L, Felmlee, D.J, Bridge, S.H, Neely, D, Cobbold, J.F, Holmes, E, Bassendine, M.F and Taylor-Robinson, S.D 2022. Infection with the hepatitis C virus causes viral genotype-specific differences in cholesterol metabolism and hepatic steatosis. Scientific Reports . 12 (5562). https://doi.org/10.1038/s41598-022-09588-w

A clinical and molecular epidemiological survey of hepatitis C in Blantyre, Malawi, suggests a historic mechanism of transmission

Stockdale, A.J, Kreuels, B, Shawa, I.T, Meiring, J.E, Thindwa, D, Silungwe, N.M, Chetcuti, K, Joekes, E, Mbewe, M, Mbale, B, Patel, P, Kachala, R, Patel, P.D, Malewa, J, Finch, P, Davis, C, Shah, R, Tong, L, Filipe, A.D.S, Thomson, E.C, Geretti, A.M and Gordon, M.A 2022. A clinical and molecular epidemiological survey of hepatitis C in Blantyre, Malawi, suggests a historic mechanism of transmission. Journal of Viral Hepatitis. 29 (4), p. 252–262. https://doi.org/10.1111/jvh.13646

Hepatitis B Vaccination Impact and the Unmet Need for Antiviral Treatment in Blantyre, Malawi

Stockdale, A.J, Meiring, J.E, Shawa, I., Thindwa, D, Silungwe, N.M, Mbewe, M, Kachala, R, Kreuels, B, Patel, P, Patel, P, Henrion, M.Y.R, Bar-Zeev, N, Swarthout, T.D, Heyderman, R.S, Gordon, S.B, Geretti, A.M and Gordon, M.A 2022. Hepatitis B Vaccination Impact and the Unmet Need for Antiviral Treatment in Blantyre, Malawi . The Journal of Infectious Diseases. 226 (5), p. 871–880. https://doi.org/10.1093/infdis/jiab562

Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines

Benedicto-Matambo, P, Bines, J.E, Malamba-Banda, Chikondi, Shawa, I., Barnes, K, Kamng'ona, A.W, Hungerford, D, Jambo, K.C, Iturriza-Gomara, M, Cunliffe, N.A, Flanagan, K.L and Jere, K.C 2022. Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines. Vaccines. 10 (3), p. 418. https://doi.org/10.3390/vaccines10030418

Rotavirus Genotypes in Hospitalized Children With Acute Gastroenteritis Before and After Rotavirus Vaccine Introduction in Blantyre, Malawi, 1997–2019

Mhango, C, Mandolo, J.J, Chinyama, E, Wachepa, R, Kanjerwa, O, Malamba-Banda, C, Matambo, P.B, Barnes, K.G, Chaguza, C, Shawa, I., Nyaga, M.M, Hungerford, D, Parashar, U.D, Pitzer, V.E, Kamng’ona, A.W, Iturriza-Gomara, M, Cunliffe, N.A and Jere, K.C 2022. Rotavirus Genotypes in Hospitalized Children With Acute Gastroenteritis Before and After Rotavirus Vaccine Introduction in Blantyre, Malawi, 1997–2019. The Journal of Infectious Diseases. 225 (12), pp. 2127 - 2136. https://doi.org/10.1093/infdis/jiaa616

Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi

Stockdale, A.J, Silungwe, N.M, Shawa, I, Kreuels, B, Gordon, M.A and Geretti, A.M 2021. Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi. BMC Infectious Diseases. 21, p. 487. https://doi.org/10.1186/s12879-021-06134-3

Reduction in Severity of All-Cause Gastroenteritis Requiring Hospitalisation in Children Vaccinated against Rotavirus in Malawi

Mandolo, J.J, Henrion, M.Y.R, Mhango, C, Chinyama, E, Wachepa, R, Kanjerwa, O, Malamba-Banda,C, Shawa, I., Hungerford, D, Kamng’ona, A.W, Iturriza-Gomara, M, Cunliffe, N.A and Jere, K.C 2021. Reduction in Severity of All-Cause Gastroenteritis Requiring Hospitalisation in Children Vaccinated against Rotavirus in Malawi. Viruses. 13 (12). https://doi.org/10.3390/v13122491

Advancing the global public health agenda for NAFLD: a consensus statement

Shawa, I. and Consortium 2021. Advancing the global public health agenda for NAFLD: a consensus statement. Nature Reviews. Gastroenterology and Hepatology. 19 (1), pp. 60-78. https://doi.org/10.1038/s41575-021-00523-4

The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?

Shawa, I. and Consortium 2021. The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge? Journal of Hepatology. 76 (4), pp. 771-780. https://doi.org/DOI:10.1016/j.jhep.2021.10.025

Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression?

Bridge, S.H., Pagano, S., Lodge, J.K., Shawa, I., Crespo, P.M, Cramp, M.E., Sheridan, D.A., Taylor-Robinson, S.D., Vuilleumier, N., Neely, R.D.G. and Bassendine, M.F. 2025. Autoantibodies to apolipoprotein A-I in hepatitis C virus infection: a role in disease progression? Frontiers in Immunology. 16, pp. 1-14. https://doi.org/10.3389/fimmu.2025.1461041

Factors affecting COVID-19 vaccine uptake in populations with higher education: insights from a cross-sectional study among university students in Malawi

Madhlopa, Q.K, Mtumbuka, M, Kumwenda, J, Illingworth, T.A, Van Hout, M, Mfutso-Bengo, J, Mikeka, C and Shawa, I.T 2024. Factors affecting COVID-19 vaccine uptake in populations with higher education: insights from a cross-sectional study among university students in Malawi. BMC Infectious Diseases. 24 (1), p. 848. https://doi.org/10.1186/s12879-024-09534-3

Drug induced liver injury - a 2023 update.

Allison, R., Guraka, A., Shawa, I., Tripathi, G., Moritz, W. and Kermanizadeh, A. 2023. Drug induced liver injury - a 2023 update. Journal of Toxicology and Environmental Health, Part B. 26 (8), pp. 1-26. https://doi.org/10.1080/10937404.2023.2261848
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