Adjanie Patabendige


Adjanie Patabendige
NameAdjanie Patabendige
Job titleAssociate Professor of Biomedical Science
Research instituteUniversity Research and Knowledge Exchange Office
ORCIDhttps://orcid.org/0000-0003-1550-3084

Research outputs

The role of the blood-brain barrier during neurological disease and infection

Patabendige, A. and Janigro, D. 2023. The role of the blood-brain barrier during neurological disease and infection. Biochemical Society Transactions. 51 (2), p. 613–626. https://doi.org/10.1042/BST20220830

Altered cerebrospinal fluid clearance and increased intracranial pressure in rats 18 h after experimental cortical ischaemia

Bothwell, S. W., Omileke, D., Hood, R. J., Pepperall, G-D., Azarpeykan, S., Patabendige, A. and Spratt, N. J. 2025. Altered cerebrospinal fluid clearance and increased intracranial pressure in rats 18 h after experimental cortical ischaemia. Brain Disease Mechanisms. 14, pp. 1-12. https://doi.org/10.3389/fnmol.2021.712779

ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma

Patabendige, A. 2023. ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma. Cancer Research. 83 (14), p. 2421–2437. https://doi.org/10.1158/0008-5472.CAN-23-0186

Blood-brain barrier disruption in dementia: Nano-solutions as new treatment options

Patabendige, A. 2023. Blood-brain barrier disruption in dementia: Nano-solutions as new treatment options. European Journal of Neuroscience. 59 (6), pp. 1359-1385. https://doi.org/10.1111/ejn.16229

Astrocytic aquaporin 4 subcellular translocation as a therapeutic target for cytotoxic edema in ischemic stroke

Patabendige, A. 2022. Astrocytic aquaporin 4 subcellular translocation as a therapeutic target for cytotoxic edema in ischemic stroke. Neural Regeneration Research. 17 (12), pp. 2666-2668. https://doi.org/10.4103/1673-5374.339481

Editorial: Cerebrospinal fluid dynamics and intracranial pressure elevation-Novel insights on molecular and physiological mechanisms, and implications for neurological disease

Patabendige, A. 2022. Editorial: Cerebrospinal fluid dynamics and intracranial pressure elevation-Novel insights on molecular and physiological mechanisms, and implications for neurological disease. Frontiers in Molecular Neuroscience. 15. https://doi.org/10.3389/fnmol.2022.1119980

Short-duration hypothermia induction in rats using Models for Studies examining clinical relevance and mechanisms

Patabendige, A. 2021. Short-duration hypothermia induction in rats using Models for Studies examining clinical relevance and mechanisms. Journal of Visualized Experiments. 169. https://doi.org/10.3791/62325

Blood-brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?

Aryal, R. and Patabendige, A. 2021. Blood-brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes? Open Biology. 11 (4). https://doi.org/10.1098/rsob.200396

Astrocyte activation in neurovascular damage and repair following ischaemic stroke

Patabendige, A. 2021. Astrocyte activation in neurovascular damage and repair following ischaemic stroke. International Journal of Molecular Sciences. 22 (8), pp. 1-22. https://doi.org/10.3390/ijms22084280

Ultra-short duration hypothermia prevents intracranial pressure elevation following ischaemic stroke in rats

Patabendige, A. 2021. Ultra-short duration hypothermia prevents intracranial pressure elevation following ischaemic stroke in rats. Frontiers in Neurology. 12, pp. 1-9. https://doi.org/10.3389/fneur.2021.684353

Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats

Patabendige, A. 2021. Short-duration hypothermia completed prior to reperfusion prevents intracranial pressure elevation following ischaemic stroke in rats. Scientific Reports. 11, pp. 1-9. https://doi.org/10.1038/s41598-021-01838-7

Decreased intracranial pressure elevation and cerebrospinal fluid outflow resistance: a potential mechanism of hypothermia cerebroprotection following experimental stroke

Patabendige, A. 2021. Decreased intracranial pressure elevation and cerebrospinal fluid outflow resistance: a potential mechanism of hypothermia cerebroprotection following experimental stroke. Brain Sciences. 11 (12), pp. 1-10. https://doi.org/10.3390/brainsci11121589

CSF secretion is not altered by NKCC1 Nor TRPV4 antagonism in healthy rats

Patabendige, A. 2021. CSF secretion is not altered by NKCC1 Nor TRPV4 antagonism in healthy rats. Brain Sciences. 11 (9), pp. 1-13. https://doi.org/10.3390/brainsci11091117
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